Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
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Year : 2004  |  Volume : 49  |  Issue : 3  |  Page : 109-116

Liposomal cancer chemotherapy in dermatology : current status and future prospects

Correspondence Address:
Uwe Wollina

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Source of Support: None, Conflict of Interest: None

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Liposomes are lamellar structures composed of a lipid bilayer. They are used as carriers for different drugs. The present paper reviews the use of intravenous liposomal anticancer drugs in dermato-oncology. The broadest application is found today for liposomal anthracyclines, i.e., doxorubicin and daunorubicin. The practical experiences with liposomal drugs in skin cancer are still limited. There is clear evidence for liposomal drug efficacy and safety in AIDS- related Kaposi’s sarcoma. Their use in other conditions, such as cutaneous T-cell lymphoma, malignant melanoma and cutaneous angiosarcoma, has been investigated in uncontrolled trials. The preliminary data, however, are promising in particular for cutaneous T-cell lymphoma.

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