Indian Journal of Dermatology
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Year : 2005  |  Volume : 50  |  Issue : 4  |  Page : 200-202

Prevalence of hepatotrophic viruses b&c in psoriasis -A study from kashmir

Department of Dermatology, STD and Leprosy Government Medical College and Associated SMHS Hospital, Srinagar, Kashmir J & K, India

Correspondence Address:
Qazi Masood Ahmad
House No. 214, Karan Nagar, Srinagar, Kashmir, (J&K)
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Source of Support: None, Conflict of Interest: None

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The association of psoriasis with hepatotrophic viruses B and C (HBV& HCV ) infection has been reported with conflicting results in literature .This association has never been investigated in Kashmir where the prevalence of psoriasis in the general population varies from 2.4 to 3.4 % and the epidemiology of chronic liver disease reveals infection with HBV and HCV to be causative in 25% and 45% of the cases respectively. The aim of this study was to determine the prevalence of HbsAg and anti- HCV antibody amongst Kashmiri patients with psoriasis. Fifty Kashmiris with psoriasis (study group) and fifty apparently healthy persons coming forward for voluntary blood donation to the hospital (control group )were screened for the presence of HbsAg by Monolisa Ag HbsAg one step enzyme immunoassay technique .The serological estimation of HCV was done by HCD 3.0 in vitro enzyme immunoassay for detection of anti HCV antibody in the serum. Two (4%) of the 50 patients in the study group were sero­positive for HbsAg and one (2%) for anti HCV. Seven (14%) of the control group were sero-positive for HbsAg and none (0%) for anti HCV. The prevalence of HbsAg in the study group comprising Kashmiri patients of psoriasis was lower than in the control group of voluntary blood donors whereas the prevalence of anti HCV was 2% in the study group against nil in the control group.Using the Chi-square test for analysis of data, the null hypothesis applies.It would appear that the prevalence of HbsAg and HCV infections in psoriasis is not statistically significant.

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