Indian Journal of Dermatology
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Year : 2010  |  Volume : 55  |  Issue : 2  |  Page : 151-156

Genetics of psoriasis and psoriatic arthritis

Division of Rheumatology, University of Toronto, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Canada

Correspondence Address:
Vinod Chandran
399 Bathurst Street, 1E-412, Toronto, Ontario, Canada M5T 2S8
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Source of Support: Vinod Chandran is supported by a Canadian institutes of Health Research Clinical Research imitative Fellowship, Henry A. Beatty scholarship from the University Health Network, Toronto, Canada and the Krembil Foundation, Canada, Conflict of Interest: None

DOI: 10.4103/0019-5154.62751

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It is well established that psoriasis and psoriatic arthritis (PsA) have a strong genetic component. Recent advances in genetics have confirmed previous associations and new loci have been discovered. However, these loci do not fully account for the high heritability of psoriasis and PsA and therefore many genetic as well as environmental factors remain to be identified. This paper reviews the current status of genetic studies in psoriasis and PsA.

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