Indian Journal of Dermatology
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Year : 2017  |  Volume : 62  |  Issue : 1  |  Page : 111
Solitary nodule on the thigh

1 Department of Dermatology, Katihar Medical College and Hospital, Katihar, Bihar, India
2 Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India

Date of Web Publication10-Jan-2017

Correspondence Address:
Dr. Anupam Das
Department of Dermatology, KPC Medical College and Hospital, Kolkata - 700 086, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.198054

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How to cite this article:
Kumar P, Das A. Solitary nodule on the thigh. Indian J Dermatol 2017;62:111

How to cite this URL:
Kumar P, Das A. Solitary nodule on the thigh. Indian J Dermatol [serial online] 2017 [cited 2022 Dec 3];62:111. Available from:

A 65-year-old apparently healthy male presented with an asymptomatic growth over the right thigh, present for the past 1 year. Initially, the lesion was a pea-sized growth which gradually increased in its dimension and morphology to attain the the present size. (2.5 cm × 3 cm). Cutaneous examination showed a solitary moist firm slightly tender nodule over the lateral aspect of the right thigh. The mass had an eroded surface, fixed to the underlying structures, and bled on touch [Figure 1]. Regional lymphadenopathy was notably absent. The mass was excised in toto and histology showed a well-circumscribed epithelial neoplasm, connected to the epidermis at multiple points. The neoplasm was composed of monomorphous cells, with several of them showing abundant pale or clear cytoplasm. Besides, there were features of ductal differentiation, cystic changes, and necrosis [Figure 2] and [Figure 3]. The stroma was characterized by thickening and hyalinization of collagen.
Figure 1: Solitary moist nodule with eroded surface on the lateral aspect of thigh

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Figure 2: Well-circumscribed neoplasm of monomorphous cells showing connections to the epidermis (H and E, ×40)

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Figure 3: Dermal tumor showing both poroid and clear cells along with ductal differentiation (H and E, ×400)

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   References Top

Ahmed TS, Priore JD, Seykora JT. Tumors of the epidermal appendages. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, Xu X, editors. Lever's Histopathology of the Skin. 10th ed. Philadelphia: Lippincott Williams and Wilkins Publishers; 2009. p. 891-2.  Back to cited text no. 1
Das A, Gayen T, Podder I, Shome K, Bandyopadhyay D. A weeping tumor in a young girl: An unusual presentation of nodular hidradenoma. Indian J Dermatol 2016;61:321-3.  Back to cited text no. 2
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Khurshid A, Yaqoob N, Devan HA, Pervez S. 'Nuclear grooves' in nodular hidradenoma: Frequency and significance of an unrecognized histopatological feature. J Cutan Pathol 2007;34:871-5.  Back to cited text no. 3
Nandeesh BN, Rajalakshmi T. A study of histopathologic spectrum of nodular hidradenoma. Am J Dermatopathol 2012;34:461-70.  Back to cited text no. 4
Lane JE, Kent DE. Malignant nodular hidradenoma treated with Mohs micrographic surgery. Cutis 2011;88:173-4.  Back to cited text no. 5


  [Figure 1], [Figure 2], [Figure 3]


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