Indian Journal of Dermatology
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Year : 2018  |  Volume : 63  |  Issue : 6  |  Page : 506-508

Acral and multicentric pigmented Bowen's disease in HIV-Positive patients: Report on two unusual cases

1 Centro De Investigación En Enfermedades Infecciosas, Instituto Nacional De Enfermedades Respiratorias, Ismael Cosío Villegas, México City, México
2 Department of Dermatology, Instituto Nacional De Ciencias Médicas Y Nutrición Salvador Zubirán, México City, México

Correspondence Address:
Dr. Monica Fernandez-Sanchez
Instituto Nacional De Enfermedades Respiratorias, Ismael Cosío Villegas, Calzada De Tlalpan 4502, Colonia Sección Xvi, C.P. 14080, Delegación Tlalpan, México City
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_47_17

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In situ squamous cell carcinoma of the skin (SCCis or Bowen's disease) is a common intraepidermal cutaneous malignancy with a low invasive potential. Acral Bowen's disease is usually solitary, but multiple acral SCCis have been reported. Pigmented Bowen's disease is typically unilesional and characterized by a hyperpigmented plaque with a velvety of keratotic surface, which can eventually simulate melanoma clinically. We describe two HIV-positive patients who presented with multiple pigmented SCCis involving the distal extremities. In patients with immunosuppression, the presence of multiple and hyperpigmented verrucae that clinically do not respond to adequate treatment should raise the differential diagnosis of SCC in situ.

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