Indian Journal of Dermatology
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Year : 2020  |  Volume : 65  |  Issue : 2  |  Page : 151-153

Hidradenoma papilliferum: Everyone else's diagnosis

Department of Dermatology, Rutgers-New Jersey Medical School, Newark, New Jersey, USA

Correspondence Address:
William Clark Lambert
Department of Dermatology, Rutgers-New Jersey Medical School, Room H576 Medical Science Building, 185 South Orange Avenue, Newark, New Jersey 07102
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_256_18

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A 52-year-old female presented with an asymptomatic cyst-like lesion on her right labia majora present for several years. Excision revealed a 3-mm cystic lesion containing complex networks of thin fronds of clear apocrine cells and basaloid cells, features characteristic of hidradenoma papilliferum (HP). In contrast to the medical literature, the lesion was connected to the overlying epithelium by a straight duct, a feature characteristic of apocrine glands. Searching of six different dermatopathology study sets revealed 11 cases diagnosed as HP. Histological review of the eight available cases for review revealed none that were diagnosed correctly. Six were syringocystadenoma papilliferum and two were trichoepithelioma. HP is a fascinating lesion that needs further study and requires better diagnostic criteria.

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