Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
Indexed with Science Citation Index (E) , Web of Science and PubMed
Users online: 3068  
Home About  Editorial Board  Current Issue Archives Online Early Coming Soon Guidelines Subscriptions  e-Alerts    Login  
    Small font sizeDefault font sizeIncrease font size Print this page Email this page

Table of Contents 
Year : 2021  |  Volume : 66  |  Issue : 1  |  Page : 87-88
An eczematous eruption on the arm

Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Tottori University Faculty of Medicine, Yonago, Japan

Date of Web Publication1-Feb-2021

Correspondence Address:
Kazunari Sugita
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Tottori University Faculty of Medicine, Yonago
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_68_19

Rights and Permissions

How to cite this article:
Sugita K, Ito A, Yamamoto O. An eczematous eruption on the arm. Indian J Dermatol 2021;66:87-8

How to cite this URL:
Sugita K, Ito A, Yamamoto O. An eczematous eruption on the arm. Indian J Dermatol [serial online] 2021 [cited 2022 Nov 29];66:87-8. Available from:

A 74-year-old Japanese man presented with a 2-year history of a pruritic eczematous eruption. The eruption occurred 3 years after he was diagnosed with chronic renal failure. He had atrial fibrillation and had been treated with warfarin for 5 years. He has a past history of childhood asthma. Clinical examination revealed itchy lichenificated and/or eczematous eruptions on the trunk and extremities [Figure 1]a. A peripheral blood sample test showed a normal leukocyte count of 6100/μl with high levels of eosinophils (2196/μl) and a high RAST index that was specific to Dermatophagoides pteronyssinus. Serum thymus and activation-regulated chemokine level was 909 (normal, <450 pg/mL), and the IgE level was normal. Dermoscopic examination showed? a round whitish area without vascular complex surrounded by small, whitish irregular areas [Figure 1]b. A skin biopsy was performed, and the site was marked with skin marking pen [Figure 1] and [Figure 2].
Figure 1: (a) There was an eczematous lesion on the upper arm. (b) Dermoscopic findings: Whitish areas without an orifice and without vessels

Click here to view
Figure 2: (a) Low-powered magnification of a histopathological specimen showed a well-defined lobule containing enlarged keratinocytes with intracytoplasmic viral inclusions (Hematoxylin and eosin [H&E] staining, 40×). (b) A high-powered view of spongiosis and perivascular infiltrate consisting of lymphocytes and eosinophils (H&E staining, 200×)

Click here to view

   Question Top

What is your diagnosis?

   Answer Top

Molluscum contagiosum.

   Discussion Top

Histopathologically, there were an acanthotic epidermis with spongiosis, and a superficial and mid-dermal perivascular inflammatory infiltrate composed of lymphocytes and scattered eosinophils. In addition, we observed a crateriform epidermal architecture containing both keratinous materials and molluscum bodies in the invaginated center. Based on these findings, we made a diagnosis of molluscum contagiosum in an eczematous background.

Molluscum contagiosum is a common skin infection caused by a poxvirus and generally occurs in children. Molluscum contagiosum lesions typically appear as single or multiple, small flesh-colored and translucent papules with a characteristic central umbilication. Since Bateman's original description, molluscum contagiosum has been considered a non-inflammatory condition both clinically and histopathologically.[1] However, several types of inflammatory reactions can occur in association with molluscum contagiosum.[2],[3] Typical dermoscopic features of molluscum contagiosum include orifices and specific vascular patterns.[4] Although the presence of an orifice is an important characteristics in identifying molluscum contagiosum,[5] our patient lacked orifices and specific vascular patterns. Thus, in case of the diagnosis remains inconclusive due to the limits of dermoscopy, histopathology can help confirm the diagnosis. Atypical clinical manifestation of molluscum contagiosum may be linked to the unique dermoscopic features. Therefore, findings of the present case and previous studies suggest that molluscum lesions can be difficult to recognize when the lesions are superimposed by eczema as well as when the lesions lack typical dermoscopic patterns of molluscum contagiosum.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

   References Top

Paterson R. Cases and observations on the molluscum contagiosum of bateman, with an account of the minute structure of the tumours. Edinb Med Surg J 1841;56:279-88.  Back to cited text no. 1
Henao M, Freeman RG. Inflammatory molluscum contagiosum. Clinicopathological study of seven cases. Arch Dermatol 1964;90:479-82.  Back to cited text no. 2
Binkley GW, Deoreo GA, Johnson HH, Jr. An eczematous reaction associated with molluscum contagiosu?m. AMA Arch Derm 1956;74:344-8.  Back to cited text no. 3
Ianhez M, Cestari Sda C, Enokihara MY, Seize MB. Dermoscopic patterns of molluscum contagiosum: A study of 211 lesions confirmed by histopathology. An Bras Dermatol 2011;86:74-9.  Back to cited text no. 4
Ku SH, Cho EB, Park EJ, Kim KH, Kim KJ. Dermoscopic features of molluscum contagiosum based on white structures and their correlation with histopathological findings. Clin Exp Dermatol 2015;40:208-10.  Back to cited text no. 5


  [Figure 1], [Figure 2]


Print this article  Email this article
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Article in PDF (905 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

    Article Figures

 Article Access Statistics
    PDF Downloaded64    
    Comments [Add]    

Recommend this journal