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Granulocyte macrophage-colony stimulating factor (GM-CSF) induced severe atypical rash in a patient of non-hodgkin's lymphoma
Gautam Kumar Singh1, Anuj Bhatnagar2, Debdeep Mitra2, Pooja Sharma1, Abhay Singh3, Barnali Mitra4
1 From the Departments of Dermatology, Venereology and Leprosy, Base Hospital Delhi Cantt, Affiliated Faculty, Army College of Medical Sciences, Delhi, India
2 Department of Dermatology, Venereology and Leprosy, Command Hospital Air Force, Bengaluru, Karnataka, India
3 Department of Dermatology, Venereology and Leprosy, Base Hospital Delhi Cantt, Delhi, India
4 Pediatrics, Base Hospital Delhi Cantt, Affiliated Faculty, Army College of Medical Sciences, Delhi, India
Correspondence Address:
Debdeep Mitra
Dermatology, Venereology and Leprosy, Base Hospital Delhi Cantt and Army College of Medical Sciences, Delhi - 110 010
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijd.ijd_66_21
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Granulocyte-macrophage colony-stimulating factor (GM-CSF) infusion has been reported with the development of transient maculopapular rash with spontaneous resolution. A 54-year-old Indian female developed intense erythematous generalised rash involving the face, trunk, extremities, palms and soles following GM-CSF infusion. Focal exudation and purpura were seen. Infusion was stopped and she was managed with a short course of systemic steroids. As yet, the development of such an atypical, severe rash following this cytokine infusion has not been reported in the literature.
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