Indian Journal of Dermatology
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Year : 2022  |  Volume : 67  |  Issue : 3  |  Page : 314

A case of acrodermatitis enteropathica mimicking mutilating palmoplantar keratoderma

1 Department of Dermatology, Pandit Raghunath Murmu Medical College and Hospital, Baripada, Odisha, India
2 Department of Dermatology, IMS and SUM Hospital, Bhubaneswar, Odisha, India
3 Consultant Niki Skin Care, Bhubaneswar, Odisha, India
4 Consultant Dermatologist, Tattva Skin and laser Clinic, Bhubaneswar, Odisha, India

Correspondence Address:
Liza Mohapatra
Assistant Professor, Department of Dermatology, IMS and SUM Hospital, Bhubaneswar, Odisha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_112_17

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Acrodermatitis enteropathica (AE) is a rare inherited form of defective zinc absorption usually manifesting as eczematous and erosive dermatitis preferably over periorificial and acral areas which at times mimics various hereditary palmoplantar keratodermas (PPK). We reported a 6-year-old boy who presented with hard plaques over both palm and sole, and periorificial areas, and flexion attitude of digits without any history of diarrhea and prolonged illness. The patient improved dramatically with zinc supplementation including correction of flexion deformities of the fingers. There was improvement of serum alkaline phosphatase level within 3 months. The lesions reappeared again whenever there was discontinuation of therapy for few weeks, thus confirming it to be zinc deficiency dermatoses. This kind of manifestation has rarely been described in earlier literature.

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