Indian Journal of Dermatology
BASIC RESEARCH
Year
: 2013  |  Volume : 58  |  Issue : 1  |  Page : 12--17

Role of skin prick test in allergic disorders: A prospective study in Kashmiri population in light of review


Roohi Rasool, Irfan Ali Shera, Saniya Nissar, Zaffar A Shah, Niyaz Nayak, Mushtaq A Siddiqi, Aga Syed Sameer 
 Department of Immunology and Molecular Medicine, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India

Correspondence Address:
Aga Syed Sameer
Department of Biochemistry, Sher-i-Kashmir Institute of Medical Sciences Associated Medical College, Bemina, Srinagar, Kashmir - 190 018
India

Background: Skin prick test (SPT) is the most effective diagnostic test to detect IgE mediated type I allergic reactions like allergic rhinitis, atopic asthma, acute urticaria, food allergy etc. SPTs are done to know allergic sensitivity and applied for devising immunotherapy as the therapeutic modality. Materials and Methods: This prospective study was conducted in the department of Immunology and Molecular medicine at SKIMS. A total of 400 patients suffering from allergic rhinitis, asthma and urticaria were recruited in this study. SPT was performed with panel of allergens including house dust mite, pollens, fungi, dusts, cockroach, sheep wool and dog epithelia. Allergen immunotherapy was given to allergic rhinitis and asthmatic patients as therapeutic modality. Results: In our study, age of patients ranged from 6 to 65 years. Majority of patients were in the age group of 20-30 years (72%) with Male to female ratio of 1:1.5. Of the 400 patients, 248 (62%) had urticaria, 108 (27%) patients had allergic rhinitis and 44 (11%) patients had asthma. SPT reaction was positive in 38 (86.4%) with allergic asthma, 74 (68.5%) patients with allergic rhinitis and 4 (1.6%) patient with urticaria, respectively. Allergen immunotherapy was effective in 58% patients with allergic rhinitis and 42% allergic asthma. Conclusion: Identifiable aeroallergen could be detected in 86.4% allergic asthma and 68.5% allergic rhinitis patients by SPT alone. Pollens were the most prevalent causative allergen. There was significant relief in the severity of symptoms, medication intake with the help of allergen immunotherapy.


How to cite this article:
Rasool R, Shera IA, Nissar S, Shah ZA, Nayak N, Siddiqi MA, Sameer AS. Role of skin prick test in allergic disorders: A prospective study in Kashmiri population in light of review.Indian J Dermatol 2013;58:12-17


How to cite this URL:
Rasool R, Shera IA, Nissar S, Shah ZA, Nayak N, Siddiqi MA, Sameer AS. Role of skin prick test in allergic disorders: A prospective study in Kashmiri population in light of review. Indian J Dermatol [serial online] 2013 [cited 2022 May 16 ];58:12-17
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2013;volume=58;issue=1;spage=12;epage=17;aulast=Rasool;type=0