SHORT COMMUNICATION
Year : 2022 | Volume
: 67 | Issue : 5 | Page : 531--534
Cross-sectional study shows an association between paediatric lichen planus and dyslipidemia
Rahul Mahajan, Dinesh Raj, Dipankar De, Sanjeev Handa
Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Correspondence Address:
Rahul Mahajan
Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh
India
Background: Few studies have shown an association between adult lichen planus and dyslipidemia, but none has shown an association with the pediatric population. We planned to study the association between pediatric lichen planus and metabolic syndrome (MS). Methodology: This is a single-centre, cross-sectional, case-control study from July 2018 to December 2019 at a tertiary care institute. Twenty children in the age group of 6–16 years, diagnosed as cases of childhood/adolescent lichen planus, and 40 age- and sex-matched controls were included in this study and evaluated for metabolic syndrome. Patients' anthropometry including weight, height, waist circumference, and body mass index (BMI) was recorded. Blood samples were sent for the measurement of fasting plasma glucose, high-density lipoprotein (HDL), low-density lipoprotein (LDL) cholesterol, and triglyceride levels. Results: The mean HDL was found to be significantly lower in children with lichen planus compared to children without lichen planus (p = 0.012), although there was no statistically significant difference in the frequency of patients having deranged HDL levels between the groups (p = 0.326). Children with lichen planus had a higher prevalence of central obesity, but the difference was not statistically significant (p = 0.101). There was no significant difference between mean BMI, hypertension, triglyceride, LDL, and fasting blood sugar values between the groups. Using the logistic regression analysis model, it was found that the strongest independent variable that impacts the occurrence of lichen planus was an HDL value less than 40 mg/dl (p = 0.017; OR 1.02 to 1.29). Conclusions and Relevance: This study shows an association between paediatric lichen planus and dyslipidemia.
How to cite this article:
Mahajan R, Raj D, De D, Handa S. Cross-sectional study shows an association between paediatric lichen planus and dyslipidemia.Indian J Dermatol 2022;67:531-534
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How to cite this URL:
Mahajan R, Raj D, De D, Handa S. Cross-sectional study shows an association between paediatric lichen planus and dyslipidemia. Indian J Dermatol [serial online] 2022 [cited 2023 Mar 29 ];67:531-534
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2022;volume=67;issue=5;spage=531;epage=534;aulast=Mahajan;type=0 |
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