E-IJDŽ - ORIGINAL ARTICLE
Year : 2022 | Volume
: 67 | Issue : 5 | Page : 624-
Clinico-epidemiology and histopathologic spectrum of primary scarring alopecia: A cross-sectional study
Souvik Sardar1, Somenath Sarkar2, Indrashis Podder3, Gautam Banerjee4
1 Dermatologist, Eleganz Skin and Hair Clinic, Kolkata, West Bengal, India
2 Department of Dermatology, Bankura Sammilani Medical College and Hospital, Bankura, West Bengal, India
3 Department of Dermatology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
4 Department of Dermatology, School of Tropical Medicine, Kolkata, West Bengal, India
Correspondence Address:
Indrashis Podder
College of Medicine and Sagore Dutta Hospital, Kamarhati, Kolkata - 700 058, West Bengal
India
Background: Primary scarring alopecias (PSAs) are a rare group of dermatological disorders with overlapping clinical features. They result in permanent hair loss and significant psychological morbidity. Aims: To analyze the clinico-epidemiology of PSAs of the scalp, along with clinico-pathological correlation. Methods: We conducted a cross sectional, observational study including 53 histopathologically confirmed cases of PSA. Clinico-demographic parameters, hair care practices, and histologic characteristics were noted and statistically analyzed. Results: Among 53 patients (mean age 30.9 ± 8.1 years, M: F 1:1.2, median duration 4 years) with PSA, lichen planopilaris (LPP) was most common (39.6%, 21/53), followed by pseudopelade of Brocq [30.2%, 16/53], discoid lupus erythematosus (DLE) [16.9%, 9/53], and non-specific scarring alopecia (SA) (7.5%, 4/53), while central centrifugal cicatricial alopecia (CCCA), folliculitis decalvans, and acne keloidalis nuchae (AKN) accounted for 1 case each. Forty-seven patients (88.7%) demonstrated predominant lymphocytic inflammatory infiltrate, while basal cell degeneration and follicular plugging were the commonest histological changes. Perifollicular erythema and dermal mucin deposition were noted in all patients with DLE (both P < 0.05). Nail involvement (P = 0.004) and mucosal involvement (P = 0.8) were more common in LPP. Single alopecic patches were characteristic of DLE and CCCA. Hair care practices (non-medicated shampoo > oil) had no significant association with the subtype of PSA. (P = 0.4) Conclusion: PSAs are a diagnostic challenge for dermatologists. Thus, histology and clinico-pathological correlation should be performed in all cases for proper diagnosis and treatment.
How to cite this article:
Sardar S, Sarkar S, Podder I, Banerjee G. Clinico-epidemiology and histopathologic spectrum of primary scarring alopecia: A cross-sectional study.Indian J Dermatol 2022;67:624-624
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How to cite this URL:
Sardar S, Sarkar S, Podder I, Banerjee G. Clinico-epidemiology and histopathologic spectrum of primary scarring alopecia: A cross-sectional study. Indian J Dermatol [serial online] 2022 [cited 2023 Mar 29 ];67:624-624
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2022;volume=67;issue=5;spage=624;epage=624;aulast=Sardar;type=0 |
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