ABSTRACT: 403 cases of vitiligo were studied with relation to age, sex, social status, geographic area of origin, occupation, educational status, food habits including alcohol intake, duration of vitiligo, family history of vitiligo, associated dermatological disorders, associated systemic diseases, size, shape, symmetry and distribution pattern of vitiligo lesions. Investigations revealed associated systemic diseases in 94 and dermatological disorders in 34 patients. Patients were treated with different drug regimens which included topical and systemic psoralens, topical and systemic steroids, combination of psoralens and steroids, systemic cyclophosphamide, systemic zinc therapy and placental extract application. Best results were achieved by combination of systemic psoralens, systemic and topical steroids. 332 patients were followed up out of which 217 recovered. Sites of repigmentation i.e. perifolicular, periphery or diffuse; and time interval of repigmentation with different regimens were also studied.

ABSTRACT: Two hundred leprosy patients consisting of one hundred tuberculoid type, ninety five lepromatous type and five cases of ENL (type II reaction) were studied for detection of Australia antigen. There was 11 percent Positivity of hepatitis B-surface antigen in lepromatous leprosy in contrast to 6 percent positivity in normal control individuals. None of the tuberculoid cases revealed the presence of Australia antigen. Association of HBs antigenemin was remarkably high (60 percent) in ENL (type II reaction)