A case of progressive symmetric erythrokeratoderma is reported for its rarity and clinical interest.

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In this prospective study, sixty patients, 28 male and 32 female aged 7 to 48 (mean 12.5) years, were divided into 3 equal groups. Patients in gr 1 applied 5% doxepin hydrochloride cream over the eczematous lesions twice daily for 2 weeks. Group II patients were treated with clobetasol propionate (0.05%) cream twice daily for 2 weeks. In gr III, the patients received topical clobetasol propionate twice daily for the first week and doxepin hydrochloride cream twice daily for the 2nd week. The improvement was measured by ‘subjective sympom’ (SS) and ‘objective sing’ (OS) scoring systems. Improvement in SS was maximum in gr III moderate in gr I and mild in gr II. Improvement in OS was maximum in gr III followed by gr II and gr I. Lichenified lesions showed no improvement. Somnolence and stinging at the local site were the adverse effects complained by 8(40%) and 3(15%) patients in gr I respectively, 2(10%) patients had both in gr III.

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Four hundred leprosy patients comprising of 140 lepromatous leprosy, 72 borderline and 188 tuberculoid leprosy patients were examined for corneal hypoaesthesia. Among them, 25 cases of lepromatous, 4 of borderline and 21 tuberculoid patients showed corneal hypoaesthesia. Upper temporal corneal area was most frequently affected. Stress is laid on health education and timely intervention.

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A case of Fox-Fordyce disease in a 21 year old female is reported because of its rarity.

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A study of 75 cases of exfoliative dermatitis showed a male preponderance (M:F=4.77:1) with highest frequency of occurrence in the fifth and sixth decades. Cutaneous ailments were responsible for 64% of cases, among which psoriasis was the commonest disease followed by various types of eczema. The syndrome was caused by drugs in 12% of the cases and malignancy in 2.67%. In 21.33% of patients the cause remained undetermined. The systemic changes and the laboratory findings are described.

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A case of periungual fibrokeratoma acquired following blunt trauma to toe, is being described. Its resemblance to koenen tumour of tuberous sclerosis and other similar lesins is discussed.

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The localization of sporotrichosis is determined by the site of dermal injury by means of which the infective spores are introduced into subcutanceous tissue, but the reports of reinfection or bilateral infection are extremely rare. Although the probability of such occurrence is high in endemic areas, the rare incidence may be due to acquired host defense, a subject of much speculation. Two such rare cases are presented and some reports of cross infections of the disease are reviewed.

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A twenty five year old female patient presented with bilateral grouped vesicular lesions with altered sensorium. It was diagnosed as herpes simplex encephalitis (type II)

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A 19 year old female was seen with multiple skin coloured and hyperpigmented macules, discrete as well as grouped papules and nodules of varying sizes distributed over the face, neck, extensor and flexor aspects of both upper and lower extremities including joints. The trunk was spared. Some of the lesions showed features of spontaneous regression. Investigations confirmed the diagnosis of juvenile xanthogranuloma. Lesions regressed satisfactorily with liquid nitrogen cryotherapy.

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Milia en plaque, an unusual clinical variant of milia, has been reported mainly in the post-auricular area. We report a case of milia en plaque over an unusual site i.e. over the angle of the mouth present over lesions of pityriasis alba.

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A case of multiple cutaneous lelomyomas is reported for its uncommon occurrence. This cases was associated with osseous and soft tissue hamartoma of right thumb, lipoma on left side of chest and back, hoarseness of voice and lower motor neurone disorder in limbs.

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A 16 year old female with facial hemiatrophy and convulsions having sparse right eyebrows and eye lashes, flattening of the nasolabial fold, protrusion of eye ball, and retraction of angle of mouth towards the affected side is reported.

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Acase of trichotillomania in a female child is presented. Unusual features in this case are early age of onset, total alopecia of the scalp and plucking the hair of the animals.

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Two cases of psoriasis under PUVA therapy presented for its unusual rapid response with quick clearance of lesions within three weeks.

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A young adult female patient of connective tissue naevus presented with papules and indurated plaques on both les and left arm. Histopathology showed increased amount of collagen in the dermis. Osteopoikilosis was absent.

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Erythrokeratoderma variabilis in an infant is described with classical clinical picture and histopathological changes. Treatment with combination of topical retinoids and steroids was observed to be effective.

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Chronic dermatophytosis caused by Trichophyton rubrum in two patients with genetic ichthyosis is being reported for its atypical manifestations leading to difficulties in diagnosis and management.

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A fifty six year old patient developed erythematcus macules, papules, annular plaques, nodules, tumours, ulcerated lesions and poikiloderma. After initial difficulty, a diagnosis of mycosis fungoides was finally made on histopathology.

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