ABSTRACT: Fortytwo cases of uncomplicated gonorrhoea in male were treated with Norfloxacin 800 mg. daily in single oral dose for 2 days and were followed up on third days ans also at the end of three weeks and six weeks. Cure rate was 100 percent and there was no relapse in cases who reported for follow-up on third and six weeks, It was found convenient in dose to the patient and superior in efficacy to conventional antibiotics used in gonorrhoea in day-to-day practice.

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ABSTRACT: A 55 year old male having papulo-nodular and verrucous lesions distributed over the extremities and a nodule in the right breast was examined and investigated. Histo-pathological examination of leg lesion and the breast nodule revealed Lichen planus hypertrophies (LPH) and carcinoma breasr (CB) respectively. During a follow up period of two years the skin lesions disappeared by local therapy and there was no recurrence of breast tumour after excision. The possible relationship of LPH and CB is discussed.

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ABSTRACT: A rare case of true benign acanthosis nigricans without evidence of any underlying disease, metabolic condition or genetic predisposition is reported

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ABSTRACT: A 52-year-old male vitiligo patient who had been on oral photochemotherapy using psoralens and sunlight for one year developed disseminated discoid lupus erythematosus lesions three years later

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ABSTRACT: In 30 vitiligo cases axon-reflex sweat secretion test with nicotine tartrate 1: 1000000 dilution and surface temperature were studied in comparison to normal adjacent skin. In 14 cases there was a decrease both in sweating and temperature and in 7 cases there was increased sweating with increase in temperature in vitiliginous area indicating an altered tone in cholinergic axon-reflex mechanism.

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