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Figure 2: (a) Bone marrow fibrosis (H and E, ×10). (b) Skin biopsy showing increased thickness of the dermis, fibrosis, and sebaceous glands hyperplasia (H and E,×2.5). (c) Bone marrow fibrosis (Masson's trichrome,×10) (d) Dermal acid mucopolysaccharides slightly increased (Colloidal iron stain,×10). (e) Elastic fibers focally reduced (Orcein ×10)

Figure 2: (a) Bone marrow fibrosis (H and E, ×10). (b) Skin biopsy showing increased thickness of the dermis, fibrosis, and sebaceous glands hyperplasia (H and E,×2.5). (c) Bone marrow fibrosis (Masson's trichrome,×10) (d) Dermal acid mucopolysaccharides slightly increased (Colloidal iron stain,×10). (e) Elastic fibers focally reduced (Orcein ×10)